When the body breaks down purines, a substance found in human tissue and in many foods, uric acid forms. Uric acid dissolves in the blood and passes through the kidneys and into urine for elimination. If the kidneys do not eliminate the uric acid properly or if there is an excessive intake of high-purine foods, uric acid begins to crystallize. This crystallized uric acid settles in the kidneys and forms kidney stones or settles into joints and causes a form of arthritis called gout. Symptoms vary between individuals, depending on the severity of the condition. Some people with high levels of uric acid may not experience any symptoms. The knee joint is perhaps one of the most important joints required for normal weight bearing of the body, irrespective of whether a person is sitting, standing or walking. It is also one of the most commonly involved joints in infections, diseases processes, trauma or application of force and other disorders that may lead to improper functioni
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