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Causes of headache

Your headache symptoms can help your doctor determine its cause and the appropriate treatment. Most headaches aren't the result of a serious illness, but some may result from a life-threatening condition requiring emergency care.

Headaches are generally classified by cause:

Primary headaches

A primary headache is caused by overactivity of or problems with pain-sensitive structures in your head. A primary headache isn't a symptom of an underlying disease.

Chemical activity in your brain, the nerves or blood vessels surrounding your skull, or the muscles of your head and neck (or some combination of these factors) can play a role in primary headaches. Some people may also carry genes that make them more likely to develop such headaches.

The most common primary headaches are:

Cluster headache

Care at Mayo Clinic (with and without aura)

Tension headache (also known as tension-type headache)

Trigeminal autonomic cephalalgia (TAC), such as cluster headache and paroxysmal hemicrania

A few headache patterns also are generally considered types of primary headache, but are less common. These headaches have distinct features, such as an unusual duration or pain associated with a certain activity.

Although generally considered primary, each could be a symptom of an underlying disease. They include:

Chronic daily headaches (for example, chronic migraine, chronic tension-type headache, or hemicranias continua)

Cough headaches

Exercise headaches

Sex headaches

Some primary headaches can be triggered by lifestyle factors, including:

Alcohol, particularly red wine

Certain foods, such as processed meats that contain nitrates

Changes in sleep or lack of sleep

Poor posture

Skipped meals

Stress

Secondary headaches

A secondary headache is a symptom of a disease that can activate the pain-sensitive nerves of the head. Any number of conditions — varying greatly in severity — may cause secondary headaches.

Possible causes of secondary headaches include:

Acute sinusitis

Arterial tears (carotid or vertebral dissections)

Blood clot (venous thrombosis) within the brain — separate from stroke

Brain aneurysm (a bulge in an artery in your brain)

Brain AVM (brain arteriovenous malformation) — an abnormal formation of brain blood vessels

Brain tumor

Carbon monoxide poisoning

Chiari malformation (structural problem at the base of your skull)

Concussion

Dehydration

Dental problems

Ear infection (middle ear)

Encephalitis (brain inflammation)

Giant cell arteritis (inflammation of the lining of the arteries)

Glaucoma (acute angle closure glaucoma)

Hangovers

High blood pressure (hypertension)

Influenza (flu) and other febrile (fever) illnesses

Intracranial hematoma (blood vessel ruptures with bleeding in or around the brain)

Medications to treat other disorders

Meningitis (inflammation of the membranes and fluid surrounding your brain and spinal cord)

Monosodium glutamate (MSG)

Overuse of pain medication

Panic attacks and panic disorder

Post-concussion syndrome

Pressure from tight headgear, such as a helmet or goggles

Pseudotumor cerebri (increased pressure inside the skull), also known as idiopathic intracranial hypertension

Stroke

Toxoplasmosis

Trigeminal neuralgia (as well as other neuralgias, all involving irritation of certain nerves connecting the face and brain)

Some types of secondary headaches include:

External compression headaches (a result of pressure-causing headgear)

Ice cream headaches (commonly called brain freeze)

Rebound headaches (caused by overuse of pain medication)

Sinus headaches (caused by inflammation and congestion in sinus cavities)

Spinal headaches (caused by low pressure or volume of cerebrospinal fluid, possibly the result of spontaneous cerebrospinal fluid leak, spinal tap or spinal anesthesia)

Thunderclap headaches (a group of disorders that involves sudden, severe headaches with multiple causes)

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